Team Lead Proposal
Tony Liang, Jeffrey Tang, Aditi Srinivasan, Sam Munn
University of British Columbia
2024-01-29
Cytokines are small intercellular signalling protein that regulate immune responses by acting on various pathways
There are two types of cytokines (Type 1 or Type 2)1:
Regulatory mechanisms in the context of cytokine induced signaling is well studied but there is limited ability to link back these cytokine induced activities on all gene expression activity partially due to short half-lives and pleiotropy2
What patterns of gene expression can be predicted from cytokine stimulation using bulk RNA sequencing data?
Other than the interleukin genes (IL-6, IL-10, IL-12, etc.), which other genes demonstrate a change in expression level when a cytokine response is triggered?
Retrieved from public database GEO1
How will you answer your main research question?
Questions?